International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
Performance of SARS-CoV-2 rapid antigen test compared with real-time RT-PCR in asymptomatic individuals.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Peña Mónica, Ampuero Manuel, Garcés Carlos, Gaggero Aldo, García Patricia, Velasquez María Soledad, Luza Ricardo, Alvarez Pía, Paredes Fabio, Acevedo Johanna, Farfán Mauricio J, Solari Sandra, Soto-Rifo Ricardo, Valiente-Echeverría Fernando
Аннотация
Screening, testing and contact tracing plays a pivotal role in control of the COVID-19 pandemic. To enable this it is necessary to increase the testing capacity. This study compared a SARS-CoV-2 rapid antigen test (RAT) and RT-PCR in 842 asymptomatic individuals from Tarapacá, Chile. A sensitivity of 69.86%, specificity of 99.61%, PPV of 94.44% and NPP of 97.22% with Ct values (Ct > 27) that were significantly higher among individuals with false-negative RAT were reported. These results support the fact that RAT might have a significant impact on the identification of asymptomatic carriers in areas that lack suitable laboratories to perform SARS-CoV-2 real-time RT-PCR diagnostics, or the results take more than 24-48 h, as well as zones with high traffic of individuals such as border/customs, airports, interregional bus, train stations or in any mass testing campaign requiring rapid results.