Circulation journal : official journal of the Japanese Circulation Society · 2009
Restored cardiac conditions and left ventricular function after parathyroidectomy in a hemodialysis patient. Parathyroidectomy improves cardiac fatty acid metabolism assessed by 123I-BMIPP.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Nanasato Mamoru, Goto Norihiko, Isobe Satoshi, Unno Kazumasa, Hirayama Haruo, Sato Tetsuhiko, Matsuoka Susumu, Nagasaka Takaharu, Tominaga Yoshihiro, Uchida Kazuharu, Murohara Toyoaki
Аннотация
A 62 year-old female hemodialysis patient underwent parathyroidectomy to treat secondary hyperparathyroidism. On the preoperative assessment, the plasma levels of parathyroid hormone (PTH) and B-type natriuretic peptide (BNP) were elevated. Echocardiography showed reduced left ventricular (LV) contraction. Myocardial iodine-123-15-(p-iodophenyl)-3-(R,S) methylpentadecanoic acid ((123)I-BMIPP) scintigraphy showed moderately reduced tracer uptake in the postero-inferior area on single-photon emission computed tomography and decreased washout on the planar images. After parathyroidectomy, the plasma levels of PTH and BNP decreased, followed by improvement in LV contraction. Myocardial (123)I-BMIPP scintigraphy revealed that the washout on planar images had increased, which suggests that myocardial (123)I-BMIPP scintigraphy is useful for estimating the effect of parathyroidectomy on cardiac function.
Предметные рубрики MeSH
BiomarkersEchocardiographyFatty AcidsFemaleHumansHyperparathyroidism, SecondaryIodine RadioisotopesIodobenzenesKidney Failure, ChronicMiddle AgedMyocardial ContractionMyocardiumNatriuretic Peptide, BrainParathyroid HormoneParathyroidectomyRadiopharmaceuticalsRecovery of FunctionRenal DialysisStroke VolumeTomography, Emission-Computed, Single-PhotonTreatment OutcomeVentricular Dysfunction, LeftVentricular Function, Left