JACC. Case reports · 2025
Endomyocarditis in Eosinophilic Granulomatosis With Polyangiitis: Cardiac Magnetic Resonance Imaging Highlights Treatment Success.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pereyra Acha Eduardo, López Gómez David, Moure Roget Cristina, González Sucarrats Silvia, Colomé Argemí Antoni, Ramírez Ruiz Jose, Sabaté Tenas Manel, Sánchez Hidalgo Antonio
Аннотация
BACKGROUND: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare vasculitis; cardiac involvement is common and worsens prognosis.
CASE SUMMARY: A 42-year-old man presented with chest pain, marked ST-T changes, eosinophilia, and elevated troponin, without obstructive coronary disease. He was diagnosed with acute eosinophilic endomyocarditis, mildly reduced left ventricular (LV) ejection fraction, and a large apical thrombus-an initial manifestation of probable EGPA. The patient received anticoagulation, corticosteroids, and immunosuppressive therapy. Endomyocardial fibrosis was confirmed via LV biopsy. During follow-up, electrocardiography and troponin T normalized, cardiac magnetic resonance (CMR) showed thrombus resolution, LV function recovery, and persistent subendocardial fibrosis.
DISCUSSION: This case illustrates severe cardiac involvement in EGPA, with serial cardiac testing including striking electrocardiogram and CMR findings.
TAKE-HOME MESSAGE: Cardiac involvement in EGPA is prevalent. Complete cardiac screening including CMR is advisable in all patients.
CASE SUMMARY: A 42-year-old man presented with chest pain, marked ST-T changes, eosinophilia, and elevated troponin, without obstructive coronary disease. He was diagnosed with acute eosinophilic endomyocarditis, mildly reduced left ventricular (LV) ejection fraction, and a large apical thrombus-an initial manifestation of probable EGPA. The patient received anticoagulation, corticosteroids, and immunosuppressive therapy. Endomyocardial fibrosis was confirmed via LV biopsy. During follow-up, electrocardiography and troponin T normalized, cardiac magnetic resonance (CMR) showed thrombus resolution, LV function recovery, and persistent subendocardial fibrosis.
DISCUSSION: This case illustrates severe cardiac involvement in EGPA, with serial cardiac testing including striking electrocardiogram and CMR findings.
TAKE-HOME MESSAGE: Cardiac involvement in EGPA is prevalent. Complete cardiac screening including CMR is advisable in all patients.