[Clinico-genealogic study of schizophrenia with a predominantly obsessive course].

A clinico-genealogic study of 66 patients with neurosis-like schizophrenia showed a certain genetic heterogeneity of schizophrenia with obsessions. In cases of an unfavourable course of the schizophrenic process in a proband (a malignant disease of obsessions), the familial background was largely determined by disturbances of the schizophrenic spectrum. In cases of a slow progression of the disease (slowly progressive pseudoneurotic schizophrenia), the hereditary background was characterized by a great variability of psychopathological manifestations. Along with schizophrenia-related abnormalities, the families of such patients featured the accumulation of constitutional anomalies, neurotic disturbances and subclinical affective disorders.