Can hypoglycaemia cause obsessions and ruminations?

Two cases of obsessional ruminations apparently secondary to functional hypoglycaemia are described. Both patients are young Caucasian males with obsessional histories at the start of dietary treatment of 18 and 6 years, respectively. In both cases, reactive hypoglycaemia was confirmed by glucose tolerance test. The first case made a complete recovery on dietary treatment which has lasted over two years; previous treatment with drugs, behaviour therapy, and counselling were unsuccessful The response of the second case has been less outstanding due to poor compliance, but improvement and worsening have been systematically related to the extent of his adherence to the suggested dietary regimen. These cases raise questions for further research on this neglected subgroup of obsessional patients.