[Effect of different factors on the induction of mimicry antigens of typhoid bacteria].

The in vitro and in vivo (white mice) studies have shown that female sex hormones, especially folliculin and hexestrol, as well as the deficiency of the T-lymphoid system of the organism in which the microbe is circulating, and also some microbial cell components accelerate the synthesis of S. typhi antigens serologically similar to the antigens of the microorganism. Antibiotics, especially oxacillin and ampicillin, sulfa drugs, especially sulfadimethoxine, inhibit antigenic mimicry in S. typhi. A suggestion is made on the interrelationship between the factors responsible for the mimicry antigens production and those for the formation of hydrogen sulfide.