Contact dermatitis · 2026
Real-Life Workup of Chronic Hand Eczema Using a Dedicated Case Report Form: A SIDAPA Multicentre Study.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
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Gallo Rosella, Guarneri Fabrizio, Hansel Katharina, Stingeni Luca, Napolitano Maddalena, Patruno Cataldo, Corazza Monica, Borghi Alessandro, Trave Ilaria, Martina Emanuela, Lauriola Maria Michela, Satta Rosanna Rita, Foti Caterina, Romita Paolo, Giuffrida Roberta, Ferrucci Silvia Mariel, SIDAPA CHE Study Group
Аннотация
BACKGROUND: Chronic hand eczema (CHE) is a challenging condition with multifactorial pathomechanisms and a wide clinical polymorphism. It is often resistant to treatments.
OBJECTIVES: To clinically and etiologically investigate CHE patients using a case report form (CRF) developed for this purpose.
METHODS: A cross-sectional study on adult patients affected by CHE was performed from January 2024 to May 2025 in 10 Italian dermatology clinics. Demographic data, clinical features, disease severity and duration, endogenous/environmental risk factors, patch test results, response to past/current treatments, and burden of disease were recorded in the dedicated CRF and analysed.
RESULTS: A total of 207 patients were enrolled in the study (mean age 41.1 ± 15.6 years), 142 (68.6%) females. CHE was moderate-severe in 58.9% of cases, refractory to topical potent corticosteroids in 81.4%. The etiological subtypes were irritant contact dermatitis in 52.7%, allergic contact dermatitis in 24.2%, and atopic dermatitis in 16.9%; clinical subtypes were identified in only 29.0% of patients, the most frequent ones being hyperkeratotic eczema (12.1%) and acute recurrent vesicular eczema (9.7%). The CRF proved to be easy to fill in and useful.
CONCLUSIONS: An accurate clinical workup can lead to CHE clinical and etiological classification in about 80% of patients and may facilitate tailored treatment strategies.
OBJECTIVES: To clinically and etiologically investigate CHE patients using a case report form (CRF) developed for this purpose.
METHODS: A cross-sectional study on adult patients affected by CHE was performed from January 2024 to May 2025 in 10 Italian dermatology clinics. Demographic data, clinical features, disease severity and duration, endogenous/environmental risk factors, patch test results, response to past/current treatments, and burden of disease were recorded in the dedicated CRF and analysed.
RESULTS: A total of 207 patients were enrolled in the study (mean age 41.1 ± 15.6 years), 142 (68.6%) females. CHE was moderate-severe in 58.9% of cases, refractory to topical potent corticosteroids in 81.4%. The etiological subtypes were irritant contact dermatitis in 52.7%, allergic contact dermatitis in 24.2%, and atopic dermatitis in 16.9%; clinical subtypes were identified in only 29.0% of patients, the most frequent ones being hyperkeratotic eczema (12.1%) and acute recurrent vesicular eczema (9.7%). The CRF proved to be easy to fill in and useful.
CONCLUSIONS: An accurate clinical workup can lead to CHE clinical and etiological classification in about 80% of patients and may facilitate tailored treatment strategies.