[Double valve replacement for infective endocarditis following osteomyelitis; report of two cases].

Infective endocarditis(IE) is relatively common but it is lethal complication of osteomyelitis. We report the case of 2 patients who had been diagnosed as IE during their conservative therapy of osteomyelitis. Both of the patients had been admitted because of severe back pain. Then IE was revealed from congestive heart failure and/or persistent fever. As several times of echocardiogram showed the progression of valvular lesion despite their antibiotic therapies, they underwent the operation of aortic and mitral valve replacements. On bacteremia-related disease like osteomyelitis, high index of suspicion and early diagnosis of IE are essential to its successful treatment.