Медицинская библиотека · Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology · 1999

[Relative analysis of the mRNA expression between endothelin and inducible nitric oxide synthase in pulpitis].

Yan Y, Lu Z

Сравнительное исследованиеАннотация на английскомСтатьяПеревод пока не подготовлен

Аннотация

OBJECTIVE

To study the relationship between endothelin-1(ET-1) and inducible nitric oxide synthase (iNOS) through the mRNA expression in pulpitis.

METHODS

The model of experimental rat pulpitis; extraction of RNA, the reverse-polymerase chain reaction(RT-PCR) were used.

RESULTS

The mRNA expression of ET-1/iNOS in pulpitis groups was higher than the control. There was relationship in the mRNA expression between ET-1 and iNOS.

CONCLUSION

Pulp microcirculation was mechanized by the contraction and relaxtion of ET-1/iNOS, which could have direct effects on the pathological change. The control mechanism was due to the up-regulation of ET-1/iNOS gene in transcription level.

Для цитирования: Yan Y, Lu Z. [Relative analysis of the mRNA expression between endothelin and inducible nitric oxide synthase in pulpitis].. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 1999.

Предметные рубрики MeSH

Animals Endothelin-1 Gene Expression Gene Expression Regulation, Enzymologic Male Nitric Oxide Synthase Nitric Oxide Synthase Type II Pulpitis RNA, Messenger Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction

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