Nursing care of an infant with atypical hemolytic uremic syndrome complicated by spontaneous bullous rupture and dystrophic wound calcification: A case report.

INTRODUCTION

Atypical hemolytic uremic syndrome (aHUS) is a rare and potentially life-threatening disease in children, and skin complications such as spontaneous bullous rupture with dystrophic wound calcification are uncommon and challenging to manage.

CASE PRESENTATION: e report the case of an 8-month-old male infant diagnosed with aHUS who developed spontaneous skin bullae rupture and subsequent dystrophic wound calcification after approximately one month of treatment, while his systemic condition was gradually improving.

NURSING IMPLICATIONS: A nurse-led multidisciplinary care approach was implemented, focusing on close monitoring of renal function, fluid balance, electrolytes, and vital signs; individualized hemodialysis support; infection prevention and medication-related observation; staged wound assessment, debridement, dressing changes, and calcification management based on moist wound healing principles; nutritional support adjusted to balance renal function and wound healing needs; pain assessment and comfort care; and continuous family education and psychological support for caregivers.

CONCLUSION

With these coordinated nursing interventions, the patient's wound gradually healed, renal function recovered, and internal homeostasis stabilized. During the 3-month post-discharge follow-up, no recurrence of aHUS was observed, and the wound condition remained satisfactory. This case highlights the importance of integrating systemic disease management with local wound care in pediatric aHUS complicated by rare wound complications and may provide practical guidance for the nursing care of similar complex pediatric cases.