Acta parasitologica · 2025
Human Leishmaniasis in Algeria: A Systematic Review and Meta-Analysis.
СтатьяСистематический обзорМетаанализНазвание и аннотация: Перевод в очереди
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Saadet Soumia, Aroussi Abdelkrim, Salhi Omar, Dahmani Ali, Ouchetati Imane, Ouchene Nassim, Khelifi Touhami Nadjet Amina
Аннотация
PURPOSE: Leishmaniasis remains a significant public health concern in Algeria, where both cutaneous and visceral forms are endemic. This systematic review aimed to assess the prevalence and spatial distribution of human leishmaniasis in Algeria, as well as the associated diagnostic methods and risk factors.
METHODS: Following PRISMA guidelines, a comprehensive literature search was conducted in Google Scholar, PubMed, ScienceDirect, and ResearchGate for studies published from January 2000 to March 2025. Eligible studies were required to focus on human leishmaniasis in Algeria and report prevalence data using cross-sectional or descriptive designs. Data were extracted on study location, sample size, diagnostic methods, and prevalence. Spatial analysis was performed using ArcGIS.
RESULTS: Thirteen studies met the inclusion criteria. Most (76.9%) focused on cutaneous leishmaniasis (CL), with a concentration of studies in northeastern Algeria. Giemsa-stained smear microscopy was the most frequently used diagnostic method (84.6%), while PCR techniques were employed in a minority of studies. The estimated regional prevalence of CL was 46.65%, with regional rates ranging from 8.7% (Constantine) to 100% (M'sila). Visceral leishmaniasis (VL) showed a prevalence of 25.8%, peaking at 92.3% in Oran. One study reported mucocutaneous leishmaniasis (MCL) with a 100% prevalence in Tizi Ouzou.
CONCLUSION: Leishmaniasis, particularly the cutaneous form, remains highly endemic in Algeria, with significant regional disparities. Continued epidemiological monitoring and the the large use of molecular diagnostic tools are essential to improve disease surveillance and control efforts.
METHODS: Following PRISMA guidelines, a comprehensive literature search was conducted in Google Scholar, PubMed, ScienceDirect, and ResearchGate for studies published from January 2000 to March 2025. Eligible studies were required to focus on human leishmaniasis in Algeria and report prevalence data using cross-sectional or descriptive designs. Data were extracted on study location, sample size, diagnostic methods, and prevalence. Spatial analysis was performed using ArcGIS.
RESULTS: Thirteen studies met the inclusion criteria. Most (76.9%) focused on cutaneous leishmaniasis (CL), with a concentration of studies in northeastern Algeria. Giemsa-stained smear microscopy was the most frequently used diagnostic method (84.6%), while PCR techniques were employed in a minority of studies. The estimated regional prevalence of CL was 46.65%, with regional rates ranging from 8.7% (Constantine) to 100% (M'sila). Visceral leishmaniasis (VL) showed a prevalence of 25.8%, peaking at 92.3% in Oran. One study reported mucocutaneous leishmaniasis (MCL) with a 100% prevalence in Tizi Ouzou.
CONCLUSION: Leishmaniasis, particularly the cutaneous form, remains highly endemic in Algeria, with significant regional disparities. Continued epidemiological monitoring and the the large use of molecular diagnostic tools are essential to improve disease surveillance and control efforts.