American journal of ophthalmology · 2024
Biomechanics Explains Variability of Response of Small Hypertropia to Graded Vertical Rectus Tenotomy.
СтатьяПоддержка исследования: вне правительства СШАПоддержка NIH: внешняя программаНазвание и аннотация: Перевод пока не подготовлен
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Kim Chang Zoo, Lim Seongjin, Demer Joseph L
Аннотация
PURPOSE: Small angle hypertropia in sagging eye syndrome is conveniently treated by graded vertical rectus tenotomy, yet an adjustable technique under topical anesthesia has been recommended because of variability of effect. We performed graded tenotomy in an experimental model to elucidate the reason for variability of response to this surgical procedure.
DESIGN: Experimental study.
METHODS: Thirty-two fresh bovine rectus musculotendon specimens were prepared including continuity with insertional sclera, and extending for a total 40 mm length to the proximal muscle bellies, and trimmed to 16 mm width. Specimens were anchored by the clamps at the scleral insertion and muscle belly ends within a physiological chamber. After preconditioning and elongation to 10% strain was imposed by a linear motor, tensile force was allowed to stabilize at a plateau state. Then 25%, 50%, 75%, 90%, and 100% marginal tenotomies were performed progressively as remnant forces were measured.
RESULTS: Tendon thickness averaged 0.29 ± 0.05 mm and width 19.71 ± 2.25 mm. On average, remnant force decreased linearly (R2 = 0.985) from 4.23 ± 1.34, 2.76 ± 0.88, 1.70 ± 0.73, 1.01 ± 0.49, 0.39 ± 0.10, and 0 N, at 0%, 25%, 50%, 75%, 90%, and 100% tenotomy. However, there was marked individual variability in effect among specimens, with coefficients of variation of 32%, 32%, 43%, 49%, and 27%, respectively.
CONCLUSION: On average, there is a linear relationship between graded rectus tenotomy and percentage force reduction, but the effect among individual tendons is large, paralleling the reported variation in surgical effect. This explains and implies continued advisability of adjustable technique in this procedure.
DESIGN: Experimental study.
METHODS: Thirty-two fresh bovine rectus musculotendon specimens were prepared including continuity with insertional sclera, and extending for a total 40 mm length to the proximal muscle bellies, and trimmed to 16 mm width. Specimens were anchored by the clamps at the scleral insertion and muscle belly ends within a physiological chamber. After preconditioning and elongation to 10% strain was imposed by a linear motor, tensile force was allowed to stabilize at a plateau state. Then 25%, 50%, 75%, 90%, and 100% marginal tenotomies were performed progressively as remnant forces were measured.
RESULTS: Tendon thickness averaged 0.29 ± 0.05 mm and width 19.71 ± 2.25 mm. On average, remnant force decreased linearly (R2 = 0.985) from 4.23 ± 1.34, 2.76 ± 0.88, 1.70 ± 0.73, 1.01 ± 0.49, 0.39 ± 0.10, and 0 N, at 0%, 25%, 50%, 75%, 90%, and 100% tenotomy. However, there was marked individual variability in effect among specimens, with coefficients of variation of 32%, 32%, 43%, 49%, and 27%, respectively.
CONCLUSION: On average, there is a linear relationship between graded rectus tenotomy and percentage force reduction, but the effect among individual tendons is large, paralleling the reported variation in surgical effect. This explains and implies continued advisability of adjustable technique in this procedure.