[Importance of cellular immunity factors in the pathogenesis of experimental balantidiasis].

Adult white rats were immunized by numerous subcutaneous injections of antigenes obtained from the cultures of B. coli and B. suis. After the rats were sensibilized they were infected with cultural forms of Balantidium. 75% of infected rats were found to have ciliates in the lumen of the large intestine. In the tissues of the intestinal wall up to the muscular layer there were observed certain pathomorphological changes such as hyperemy, oedema, haemorrhagia and ulcers. By means of the macrophaga migration test it was established that in rats during their immunization and following infection appear lymphocytes which are sensibilized in relation to the balantidial antigene that points to the formation of slow allergy in their organisms.