The resolution of endoperiodontal lesions. New treatment protocol and time sequencing.

Endoperiodontal lesions (EPLs) are defined as an acute or chronic condition in which both the pulp and periodontal tissue are infected, resulting in deep periodontal pockets that may be a very challenging scenario for clinicians. No clear protocol has been established to date for the complete resolution of these cases. The aim of the present article is to present a new interdisciplinary treatment protocol that reduces the time interval between the nonsurgical periodontal and endodontic treatment and the periodontal regeneration surgery. Two clinical reports of EPLs are described. During Step I periodontal therapy, endodontic treatment was also performed. Six weeks later, Step II periodontal therapy by means of periodontal regeneration surgery was achieved. After 12 and 42 months, periodontal pocket depth reduction, clinical attachment level gain, and radiographic bone fill of the areas involving the EPLs were observed. Reducing the time interval between the nonsurgical periodontal and endodontic treatment and the periodontal regeneration surgery may be beneficial in these complex scenarios.