Keep Up the Good (Bench) Work!

Professor Silvia Moreno studies toxoplasmosis, one of the most common parasitic infections in the world, caused by Toxoplasma gondii. About one-third of the human population is chronically infected with T. gondii cysts, the dormant form of the parasite. Although most immunocompetent infected individuals remain asymptomatic throughout life, serious complications such as loss of vision, mother-to-fetus transmission, and fatal cases can occur. The drugs currently available to treat toxoplasmosis are unable to clear the cyst form of the parasite and have severe side effects like bone marrow suppression and liver toxicity. Silvia has studied parasite metabolism for more than 20 years and has been at the University of Georgia since 2005. Her goal is to uncover unique aspects of parasite metabolism that can be targeted for designing more effective, less toxic drugs against T. gondii. In this short interview, Silvia highlights the importance of staying true to one's identity and of learning to say 'no', and advises young researchers to not stay away from the bench.