[Vaccination against papillomavirus : outstanding issues].

Vaccination against papillomavirus: outstanding issues. Human papillomavirus or HPV are oncogenic viruses involved in many cancers. It is estimated that around 5% of cancers worldwide are linked to HPV infection. Cancers of the cervix, vagina, vulva, anus, penis and throat (tonsil) are virally induced in proportions ranging from 35 to almost 100%. These cancers are not all easily detected and the detection of lesions is not always simple and effective. Prophylactic anti-HPV vaccination is recognized for its effectiveness in the prevention of cervical cancers, its place in the prevention of other induced HPV cancers remains debated.