Glycated hemoglobin targets and glycemic control: Link with lipid, uric acid and kidney profile.

AIMS: To compare uric acid, lipid, and kidney profile along with management and complications of Indonesian diabetic patients with good and poor glycemic control based on glycated hemoglobin profile.

MATERIALS AND

METHODS

Data was obtained from medical records of Internal Medicine Clinic in Hermina Podomoro General Hospital for the period January-December 2015. Subjects were grouped into good and poor glycemic control groups based on their glycated hemoglobin (HbA1c) levels.

RESULTS

Fifty-five subjects were obtained with an average age of 54 years, 29 with good glycemic control and 26 with poor glycemic control. All glycemic parameters were worse in poor compared to good glycemic control group (p < 0.05). Similar averages of urea, creatinine, uric acid, low-density lipoprotein (LDL) and a lower average of high-density lipoprotein (HDL) were found between both groups with statistically non-significant differences (p > 0.05). Main comorbidities were dyslipidemia, hypertension, and nephropathy. Fatty liver disease, urinary tract infection and neuropathy was also reported. Most patients were prescribed with oral anti-diabetics.

CONCLUSION

Diabetic patients regardless of glycemic control according to current guidelines have a greater average lipid and kidney profile than the optimum target. Therefore both are equally at greater risk for cardiovascular diseases, nephropathy, and other diabetic complications. Greater patient monitoring of these parameters is recommended to lower the risk of comorbidities and complications.