Wegener's granulomatosis of the orbit: a review of clinical features and updates in diagnosis and treatment.

Wegener's Granulomatosis (WG) is an uncommon systemic vasculitic disease involving the respiratory system and kidneys. It is the most common antineutrophil cytoplasm antibody (ANCA)-associated vasculitis. Orbital involvement in WG is a rare but potentially devastating disorder leading to visual loss and deformity. Most clinical characteristics of this disease are non-specific, making clinical diagnosis nearly impossible. We reviewed the features of WG involving the orbit including radiologic, serologic, and histopathologic findings. Advances in treatment are likewise discussed.