Structural and functional involvement of pituitary gland in Wegener's granulomatosis.

A case of involvement of the pituitary gland in Wegener's granulomatosis in a patient with diabetes inspidus and hyperprolactinemia is presented. Initial magnetic resonance imaging (MRI) revealed loss of normal high signal in the posterior pituitary on T1-weighted images (T1WI) while the anterior pituitary was enlarged showing a central low signal intensity area on T1WI and high signal intensity on T2WI. Repeated MRI after treatment showed almost complete radiological resolution of these abnormalities along with clinical improvement.