[Pheochromocytoma - Disease Model for Personalized Medicine].

Pheochromocytomas and paragangliomas (PPGL) can be related to a uniquely high rate of underlying germline and somatic mutations. Accordingly, they can be assigned into genetic clusters, which are related to a specific biochemical and clinical phenotype as well as a different long term prognosis. The present article discussed how emerging knowledge on the respective clusters allows individual patient management before, during and after occurrence of a PPGL to improve clinical outcome.