[Prevention and treatment of low-dose aspirin induced gastric ulcer in coronary artery disease after coronary intervention].

Low-dose aspirin has been increasingly used to prevent cardiovascular and cerebrovascular disease through its antiplatelet effect, mainly in the patients with ischemic heart disease, but aspirin has been associated with gastrointestinal injuries, especially peptic ulcer bleeding. However, discontinuation of aspirin may cause cardiovascular and cerebrovascular events. Therefore, high-risk patients for peptic ulcers should be prevented with anti-secretory drugs, such as proton pump inhibitor of H2-receptor antagonists, because ulcer bleedings in patients with treatment of low-dose aspirin can be serious.