Utility of continuous glucose monitoring in people with type 2 diabetes on insulin-based regimens in clinical practice: A case series and expert opinion.

In individuals with type 2 diabetes (T2D) on insulin, continuous glucose monitoring (CGM) provides feedback on intra- and inter-day glycaemic variations that helps tailor the insulin regimen and lifestyle choices, without the pain of multiple finger pricks. However, practical guidance on the use of CGM in this cohort is limited in Asia. In this case series-based review and expert opinion paper, we aim to provide expert guidance, through a case-based approach, on the use of CGM in people with T2D on insulin therapy, primarily in three profiles: (1) individuals with no comorbidities; (2) those with comorbid cardiovascular risk factors; and (3) elderly individuals with T2D on insulin. Five anonymised demonstrative real-world cases, including ambulatory glucose profiles, have been presented. The benefits of CGM in T2D management in each profile as well as supporting literature are discussed and ten key clinical practice points are proposed to aid in optimising the use of CGM for achieving glycaemic targets, adjusting insulin therapy, motivating adherence to lifestyle intervention, reducing the risk of, or minimising the duration of, hypoglycaemia, and improving the overall quality of life and well-being in this population.