[Curative effects of basic fibroblast growth factor on anus wound healing].

OBJECTIVE

To observe the curative effects of basic fibroblast growth factor (bFGF) on anus wound healing.

METHODS

From April 1996 to December 2000, out of 109 patients with anus trauma, hemorrhoidectomy or fistula resection, 68 were treated with bFGF as the experimental group, while 41 were treated routinely as the control group. The healing of the wound, the general and local reaction were observed.

RESULTS

The healing time of the experimental group was(17.00 +/- 1.54) days while that of the control group was(20.00 +/- 1.16) days (P < 0.01). Three weeks after operation, the healing rates of the experimental and control groups were 97.1% and 87.8%, respectively (P < 0.01). No general or local detrimental reactions were found in two groups.

CONCLUSION

Local application of bFGF can accelerate the healing of anus wound, and the patients have little pain.