Generalized Bullous Fixed-Drug Eruption in a 15-Year-Old Child With Becker Muscular Dystrophy and Epilepsy.

INTRODUCTION

Generalized bullous fixed drug eruption (GBFDE) is a potentially life-threatening condition, typically triggered by a range of medications. Its incidence in the pediatric population is exceedingly low.

CASE SUMMARY: We present a 14-year-old boy with a complex medical history, including Becker muscular dystrophy and epilepsy, who experienced recurrent episodes of GBFDE over the past 2 years. The episodes culminated in a severe presentation resembling Stevens-Johnson syndrome. Detailed evaluation identified ibuprofen as the culprit drug. The patient was treated with prednisone, commencing at a dose of 0.5 mg/kg and tapered over a 2-week period, which resulted in a significant regression of lesions.

CONCLUSION

In cases with multiple potential drug triggers, it is essential to identify common drug classes associated with GBFDE and monitor the onset of symptoms post-ingestion. Our findings support the effective and safe use of prednisone, highlighting a generally positive prognosis for pediatric patients with this condition. &nbsp.