Three-dimensional volume estimates of pancreatic fluid collections in relation to clinical outcomes of endoscopic ultrasound-guided treatment.

BACKGROUND AND AIMS: The 3-dimensional (3D) volume of a pancreatic fluid collection (PFC) has not been fully investigated in EUS-guided treatment.

METHODS

In 372 patients, we examined the 3D volume in relation to the clinical outcomes.

RESULTS

In walled-off necrosis, 3D volume was associated with time to clinical success and in-hospital mortality with a multivariable subdistribution hazard ratio of 0.43 (95% CI, 0.28-0.66; Ptrend = .010) and a multivariable odds ratio of 30.9 (95% CI, 4.31-222; Ptrend = .004), respectively (for ≥1000 cm3 vs < 250 cm3). In pseudocysts, 3D volume was associated with in-hospital mortality (Ptrend = .014) with a multivariable odds ratio of 12.5 (95% CI, 0.81-193; for ≥500 cm3 vs < 100 cm3). The maximum diameter represented a comparable model goodness-of-fit.

CONCLUSIONS

PFC volume was associated with the outcomes of EUS-guided interventions, and the maximum diameter may be a reasonable surrogate.