Day zero of autologous cryopreserved hematopoietic stem cell transplantation: microcosting of care provided by senior nurses.

OBJECTIVE

To measure the average direct cost of care provided by senior nurses to patients on day zero of autologous, cryopreserved hematopoietic stem cell transplantation in a public transplant hospital in the state of São Paulo.

METHOD: Quantitative, exploratory-descriptive, single-case study based on bottom-up micro-costing, conducted from February to April 2025.

RESULTS

Twenty-eight procedures performed by senior nurses on 16 patients on day zero of the transplant were observed, covering the pre-infusion (n = 718), intra-infusion (n = 375), and post-infusion (n = 463) phases of hematopoietic stem cell transplantation. In the pre-infusion phase of hematopoietic stem cell transplantation, the total average direct cost was US$59.52; in the intra-infusion phase, US$663.45; and in the post-infusion phase, US$16.84. The average direct cost of nursing labor predominated in all three phases. However, in the intra-infusion phase, the cost of supplies was the largest contributor to the total average direct cost.

CONCLUSION

Considering the three phases (n = 1556 observations), the total average direct cost was US$739.81 (100.00%), with 8.04% related to the pre-infusion phase, 89.68% to the intra-infusion phase, and 2.28% to the post-infusion phase.