Muscle & nerve · 2015
Properties of the tibialis anterior muscle after treatment with laser therapy and natural latex protein following sciatic nerve crush.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Muniz Kenia Lemos, Dias Fernando José, Coutinho-Netto Joaquim, Calzzani Ricardo Alexandre Junqueira, Iyomasa Mamie Mizusaki, Sousa Luiz Gustavo De, Santos Thais Tedeschi Dos, Teles Vanessa De Oliveira, Watanabe Ii-Sei, Fazan Valéria Paula Sassoli, Issa João Paulo Mardegan
Аннотация
INTRODUCTION: In this study we evaluated the characteristics of the tibialis anterior muscle after sciatic nerve crush and treatment with low-level laser therapy (LLLT) or the protein from natural latex (P1).
METHODS: We studied the following 6 groups of male Wistar rats: control (CG); exposed nerve (EG); injured nerve (IG); injured nerve with LLLT (LG); injured nerve with P1 (PG); and injured nerve with P1 and LLLT (LPG).
RESULTS: After 4 weeks, muscle morphology showed improvement in the treated groups; after 8 weeks, the treated groups resembled controls, especially the PG. Morphometry revealed muscle fiber atrophy after nerve injury, with time-dependent recovery. Histochemical analysis revealed increased intermediate fiber area. The PG was more similar to controls with NADH staining, whereas the LPG more closely resembled controls with SDH staining.
CONCLUSION: Treatment using only P1 proved most efficient, revealing a negative interaction between P1 and LLLT.
METHODS: We studied the following 6 groups of male Wistar rats: control (CG); exposed nerve (EG); injured nerve (IG); injured nerve with LLLT (LG); injured nerve with P1 (PG); and injured nerve with P1 and LLLT (LPG).
RESULTS: After 4 weeks, muscle morphology showed improvement in the treated groups; after 8 weeks, the treated groups resembled controls, especially the PG. Morphometry revealed muscle fiber atrophy after nerve injury, with time-dependent recovery. Histochemical analysis revealed increased intermediate fiber area. The PG was more similar to controls with NADH staining, whereas the LPG more closely resembled controls with SDH staining.
CONCLUSION: Treatment using only P1 proved most efficient, revealing a negative interaction between P1 and LLLT.