[Predicting the recurrence of thyrotoxicosis after iodine radioisotope therapy of diffuse toxic goiter].

Prediction of a recurrence of thyrotoxicosis during radioiodine therapy of patients with diffuse toxic goiter (DTG) is a pressing problem of everyday treatment of such patients. Altogether 43 DTG patients were investigated during 12-18 mos. after 131I therapy with the determination of T4, T3, bTSH, delta TSH in the TRH test, peripheral blood rosette forming (RFC), migration index (MI) in the leucocyte migration inhibition reaction, and serum immunoglobulins (IgA, M, G). Changes in the immunological status in parallel with confirmation of autonomous thyroid functioning suggested higher risk of a thyrotoxicosis recurrence making it possible to differentiate the type of observation of a DTG patient following radioiodine therapy. The availability of the above tests allows their use for the prediction of recurrences in everyday clinical practice during therapy of DTG patients with 131I.