[Endotoxicosis in surgery].

The question of general toxemia as an important problem in acute surgery has first been raised. In addition to the infection component attention is called to the presence of a pathologic focus (diseased internal organ) which is the main cause of diffuse peritonitis. Attention is given to sepsis and basedowian goiter with the IV degree thyrotoxicosis followed by pronounced toxemia. In addition to antibacterial therapy the authors recommend transfusion of fresh blood with heparin, forced diuresis, peritoneal dialysis hemosorption, ganglionic blockade with venous antiseptics and other methods to struggle against toxemia. The active tactics of the surgeon is necessary aimed at elimination of the main cause of general toxemia--liquidation of the pathological focus.