[Mechanisms of hormonal regulation of blood glucose in thyrotoxicosis].

Rabbits with thyrotoxicosis develop at the early stages of this pathology hyperglycemia, and, as the disease persisted and grew more severe, hypoglycemia. The insulin level in the peripheral blood decreases progressively in the time course of thyrotoxicosis; insulin response to glucose, a specific stimulus, also weakens. The idea of glucose utilization by muscles regardless of the insulin effect is postulated basing on analysis of the authors' and literature data. Its main physiological function in the body is supposed to be the inhibition of glucose production by the liver and free fatty acids by the adipose tissue.