Evaluation of a 10 percent carbamide peroxide gel vital bleaching agent.

A clinical study determined the whitening effect of a 10 percent carbamide peroxide gel on the teeth of 10 subjects. Histological evaluation of the effect of this agent on human tooth pulps and hamster cheek pouch tissues was also undertaken. The gel provided a modest, but unpredictable, whitening of discoloured teeth. A localised mild to moderate inflammatory response was found in some of the pulps of teeth that had been bleached. No soft-tissue changes were observed in the hamster cheek pouches.