[Clinical presentation, diagnosis, and treatment of ocular manifestations of generalized and secondary focal yersiniosis].

The article describes possible clinical presentation, diagnosis, and treatment of ocular manifestations of generalized and secondary focal yersiniosis. Treatment experience of 32 patients (60 eyes) with episcleritis, scleritis, chorioretinitis, and anterior and posterior uveitis associated with generalized and secondary focal yersiniosis is reviewed. In order to clarify disease etiopathogenisis conventional ophthalmic assessment as well as clinical and immunological laboratory tests, including HLA typing, were performed. All patients also consulted an infectiologist, rheumatologist, urologist, gynecologist, etc. Treatment strategy implied the use of anti-infectious and anti-inflammatory agents, antisensitizers, and drugs capable of improving intracellular immunity, therapy staging, and providing a comprehensive effect on different components of the pathologic process. Due to polymorphism of yersiniosis, all patients with autoimmune eye diseases are to be tested for specific antibodies to Yersiniae.