Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022
An affordable implantable vagus nerve stimulator system for use in animal research.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Canal-Alonso Ángel, Casado-Vara Roberto, Castellano Orlando, Herrera-Santos Jorge, Gonçalves Jaime, Màrquez-Sànchez Sergio, Gonçalves Jesús María, Corchado Juan Manuel
Аннотация
In this research, a vagus nerve stimulator has been developed and miniaturized for use in epilepsy research. The board contains all the components necessary for its operation during the standard duration of the experiments, being possible to control it once implanted and even being able to reuse it. The VNS system has been designed for rodents since the VNS devices available for human are not only too large for laboratory animals, but also too expensive. With this solution the expenditure on materials made by laboratories is greatly reduced and bioethical considerations were kept in mind. The system was validated in hamsters. This article is part of the theme issue 'Advanced neurotechnologies: translating innovation for health and well-being'.