[Oral aphthoid toxic dermatoses].

In a description of 4 cases (phenindione, 1 case; niflumic acid, 1 case; gold salts, 2 cases), the authors describe a new variety of oral toxicodermatitis characterized by an eruption of painful, infiltrated aphthoid ulcerations, not precededbybull ae, small (less than 1 cm), roundish, with a greyish yellow necrotic centre surrounded by an erythematous halo. Histological investigation reveals a compact, polymorphous inflammatory infiltrate with numerous polynuclear neutrophiles or, less commonly, eosinophiles some of which are in a state of pyknosis of leukocytoclasia, associated with phenomena of spongiosis or necrosis of the epithelium.