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DOI 10.1038/s41585-026-01137-8

Медицинская библиотека · Nature reviews. Urology · 2026

Active surveillance in low-grade NMIBC - results of an international two-round modified Delphi consensus.

Contieri Roberto, Gontero Paolo, Hurle Rodolfo, Afferi Luca, Albisinni Simone, Babjuk Marek, Birtle Alison, Black Peter, Brausi Maurizio, Bruins Max, Čapoun Otakar, Carrion Albert, Catto James, Choudhury Ananya, Cimadamore Alessia, Comperat Eva, Daneshmand Siamak, D'andrea David, Del Giudice Francesco, Escrig Jose Luis Domínguez, Hensley Patrick, Krajewski Wojciech, Laukhtina Ekaterina, Li Roger, Liedberg Fredrik, Lotan Yair, Marcq Gautier, Mariappan Paramananthan, Mari Andrea, Martini Alberto, Lecomte Alexandra Masson, Meijer Richard, Mir Maria Carmen, Mori Keiichiro, Moschini Marco, Mostafid Hugh, O'Donnell Micheal, Palou Joan, Panebianco Valeria, Perdonà Sisto, Porten Sima, Psutka Sarah, Rink Michael, Roupret Morgan, Seisen Thomas, Soloway Mark, Soukup Viktor, Steinberg Gary, Stenzl Arnulf, Teoh Jeremy Yc, Tully Karl, van der Heijden Toine, van Rhijn Bas W G, Witjes Alfred, Xylinas Evanguelos, Kamat Ashish M, Pradere Benjamin, Mertens Laura S

Consensus StatementСтатьяПеревод пока не подготовлен

Аннотация

Standard management for recurrent low-grade non-muscle-invasive bladder cancer (LG-NMIBC) often involves a substantial treatment burden, which is not justified by the relatively indolent course of the disease, prompting a need for de-intensification strategies. Active surveillance (AS) is an alternative approach aimed at reducing overtreatment in selected patients. However, the broader adoption of AS is hindered by a lack of standardized protocols for patient selection, monitoring and intervention. To address this gap, we conducted an international, two-round Delphi consensus among 51 bladder cancer experts to establish foundational statements for the use of AS. Consensus was achieved on 20 statements, providing clear recommendations for terminology; inclusion and exclusion criteria; follow-up monitoring; and exit criteria. This Delphi consensus provides the first expert-driven framework to standardize the clinical application of AS for LG-NMIBC. These statements could guide current clinical practice and unify the design of future trials.

Для цитирования: Contieri Roberto, Gontero Paolo, Hurle Rodolfo, Afferi Luca, Albisinni Simone, Babjuk Marek, Birtle Alison, Black Peter, Brausi Maurizio, Bruins Max, Čapoun Otakar, Carrion Albert, Catto James, Choudhury Ananya, Cimadamore Alessia, Comperat Eva, Daneshmand Siamak, D'andrea David, Del Giudice Francesco, Escrig Jose Luis Domínguez, Hensley Patrick, Krajewski Wojciech, Laukhtina Ekaterina, Li Roger, Liedberg Fredrik, Lotan Yair, Marcq Gautier, Mariappan Paramananthan, Mari Andrea, Martini Alberto, Lecomte Alexandra Masson, Meijer Richard, Mir Maria Carmen, Mori Keiichiro, Moschini Marco, Mostafid Hugh, O'Donnell Micheal, Palou Joan, Panebianco Valeria, Perdonà Sisto, Porten Sima, Psutka Sarah, Rink Michael, Roupret Morgan, Seisen Thomas, Soloway Mark, Soukup Viktor, Steinberg Gary, Stenzl Arnulf, Teoh Jeremy Yc, Tully Karl, van der Heijden Toine, van Rhijn Bas W G, Witjes Alfred, Xylinas Evanguelos, Kamat Ashish M, Pradere Benjamin, Mertens Laura S. Active surveillance in low-grade NMIBC - results of an international two-round modified Delphi consensus.. Nature reviews. Urology. 2026. DOI: 10.1038/s41585-026-01137-8.

Предметные рубрики MeSH

HumansConsensusDelphi TechniqueNeoplasm GradingNon-Muscle Invasive Bladder NeoplasmsUrinary Bladder NeoplasmsWatchful Waiting
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