Dutch Christian Faith Leaders Deliberating Human Germline Gene Editing: A Qualitative Study.

While human germline gene editing (HGGE) is not allowed, the World Health Organization and others called for public dialogue to clarify the values at stake. Some values may be rooted in religion, such as Christianity, and relevant to religious communities and wider society. In-depth interviews (N = 16) were conducted with Dutch Christian faith leaders in 2019 and 2024. Participants were asked about their views and underlying values, their possible approaches in pastoral counselling and their recommendations for future legislation regarding HGGE. Reflexive thematic analysis was used to analyze the interviews. The findings of this study firstly showed that participants' views on the (un)acceptability of HGGE were underpinned by six values: human dignity; humility; alleviation of suffering; acceptance; compassion and justice. Secondly, regarding pastoral counselling, participants indicated that they would try to support the person(s) in need unconditionally regardless of their church teachings and/or their own values regarding HGGE. At the same time, their values would guide a thoughtful reflection on someone's motivation behind using HGGE. Finally, regarding future legislation, participants call for great caution and for legislation against human enhancement. They worry about a slippery slope from individual 'therapeutic' cases to unwanted expansions. This study contributes to a better understanding of values that lead to views regarding HGGE, which is relevant for dialogues and policymaking.