The Lancet. Neurology · 2017
Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria.
СтатьяПоддержка исследования: вне правительства СШАОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Thompson Alan J, Banwell Brenda L, Barkhof Frederik, Carroll William M, Coetzee Timothy, Comi Giancarlo, Correale Jorge, Fazekas Franz, Filippi Massimo, Freedman Mark S, Fujihara Kazuo, Galetta Steven L, Hartung Hans Peter, Kappos Ludwig, Lublin Fred D, Marrie Ruth Ann, Miller Aaron E, Miller David H, Montalban Xavier, Mowry Ellen M, Sorensen Per Soelberg, Tintoré Mar, Traboulsee Anthony L, Trojano Maria, Uitdehaag Bernard M J, Vukusic Sandra, Waubant Emmanuelle, Weinshenker Brian G, Reingold Stephen C, Cohen Jeffrey A
Аннотация
The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in research and clinical practice. Scientific advances in the past 7 years suggest that they might no longer provide the most up-to-date guidance for clinicians and researchers. The International Panel on Diagnosis of Multiple Sclerosis reviewed the 2010 McDonald criteria and recommended revisions. The 2017 McDonald criteria continue to apply primarily to patients experiencing a typical clinically isolated syndrome, define what is needed to fulfil dissemination in time and space of lesions in the CNS, and stress the need for no better explanation for the presentation. The following changes were made: in patients with a typical clinically isolated syndrome and clinical or MRI demonstration of dissemination in space, the presence of CSF-specific oligoclonal bands allows a diagnosis of multiple sclerosis; symptomatic lesions can be used to demonstrate dissemination in space or time in patients with supratentorial, infratentorial, or spinal cord syndrome; and cortical lesions can be used to demonstrate dissemination in space. Research to further refine the criteria should focus on optic nerve involvement, validation in diverse populations, and incorporation of advanced imaging, neurophysiological, and body fluid markers.