Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) · 2021
[Correlation between insufficiency or deficiency of vitamin D levels and interleukins 1β and 6].
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Zavala-Jonguitud Luis Fernando, Anda Juan Carlos, Flores-Padilla Miguel Guillermo, Pérez Carla, Juárez-Villa José Daniel
Аннотация
OBJECTIVES: The primary objective of this study was to define the relationship between vitamin D levels and interleukins (IL) 1β and 6 as inflammatory markers in a healthy population. As a secondary objective, to measure the prevalence of insufficiency/ deficiency of vitamin D in the same population.
METHODS: A sample of 43 healthy blood donors, without chronic-degenerative, inflammatory, or infectious diseases, and without obesity, was selected. Serum levels of IL-1β and IL-6 were measured in individuals with insufficiency or deficiency of vitamin D. The correlation between vitamin D and interleukins was measured using Spearman's rho.
RESULTS: No correlation was found between levels of vitamin D and interleukins. In addition, a prevalence of insufficiency/deficiency of vitamin D was found in 95.3% of the sample.
CONCLUSIONS: In healthy subjects with deficiency or insufficiency of vitamin D, there is no association between the levels of this vitamin and IL-1β and IL-6.
METHODS: A sample of 43 healthy blood donors, without chronic-degenerative, inflammatory, or infectious diseases, and without obesity, was selected. Serum levels of IL-1β and IL-6 were measured in individuals with insufficiency or deficiency of vitamin D. The correlation between vitamin D and interleukins was measured using Spearman's rho.
RESULTS: No correlation was found between levels of vitamin D and interleukins. In addition, a prevalence of insufficiency/deficiency of vitamin D was found in 95.3% of the sample.
CONCLUSIONS: In healthy subjects with deficiency or insufficiency of vitamin D, there is no association between the levels of this vitamin and IL-1β and IL-6.