[Role of the change of daily rhythms of adrenaline and noradrenaline concentration in blood in the mechanism of accelerated aging in hypopinealizm induced by a long period of day and night lighting].

In young adult male rabbits circadian rhythms change of blood concentrations of adrenaline and noradrenaline in the dynamics of hypopinealism development induced by a long period (5 months) twenty-four-hour lighting of low intensity (30-40 lux) were studied. It was found that the light in the night leads to a significant increase in the levels of both catecholamines, which indicates on the activation of the sympathoadrenal system (SAS), just as it occurs in aging and stress (stress-age-syndrome by V.V. Frolkis). Daily features of SAS reactions to light stress were revealed. Based on these data it can be concluded that one of the reduction mechanisms of life expectancy at hypopinealizm is excessive and prolonged activation of SAS.