[Poikilodermatous mycosis fungoides].

Poikilodermatous mycosis fungoides is a rare variant of mycosis fungoides (MF), characterized by a distinctive triad of epidermal atrophy, reticulated coalescing erythematous papules or plaques, and telangiectasia. Histologically, a band-like infiltrate of epidermotropic atypical lymphocytes can be observed. Diagnostic differentiation from other poikilodermatous dermatoses is challenging due to overlapping clinical and histopathological features. We present the case of a 66-year-old woman with slowly progressive cutaneous lesions on the trunk over a period of 6 years, whose definitive diagnosis was only established through serial skin biopsies and immunohistochemical analyses. This case underscores the diagnostic challenges and highlights the importance of close clinicopathological correlation.