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DOI 10.4067/s0716-10182019000600767

Медицинская библиотека · Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia · 2019

[First isolation de Candida auris in Chile].

Moreno María Victoria, Simian María Elvira, Villarroel Javier, Fuenzalida Luz María, Yarad María Fernanda, Soto Andrés, Silva Verónica, Pimentel Ximena

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Аннотация

Candida auris is an emerging multi-drug-resistant fungus that is rapidly spreading worldwide. Since the first reports in 2009, many isolates across five continents have been identified as agents of hospital-associated infections. Independent and simultaneous outbreaks of C. auris are becoming a major concern for healthcare and scientific community. Moreover, laboratory misidentification and multi-drug-resistant profiles, rarely observed for other non-albicans Candida species, result in difficult eradication and frequent therapeutic failures of C. auris infections. In this article we present the first case of isolation of a strain of C. auris at a hospital in Santiago, in a patient coming from India, who was admitted for treatment of diabetic foot complications. The strain was recovered from a tissue culture and identified by VITEK® 2 Compact. The accurate identification of C. auris was confirmed by means of MALDI-TOF MS and DNA sequence analysis. The isolate was resistant to fluconazole, retaining only susceptibility to amphotericin and caspofungin with MIC breakpoints recommended by CDC. The emergence of C. auris is alarming because the mode of transmission within the healthcare environment is not clear and is likely to be multifactorial.

Для цитирования: Moreno María Victoria, Simian María Elvira, Villarroel Javier, Fuenzalida Luz María, Yarad María Fernanda, Soto Andrés, Silva Verónica, Pimentel Ximena. [First isolation de Candida auris in Chile].. Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia. 2019. DOI: 10.4067/s0716-10182019000600767.

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