Медицинская библиотека · Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022

HIPEC with CRS versus cytoreductive surgery (CRS) for the gastric cancer metastasis to peritoneum.

Chen Zhuming, Ali Muhammad, Kai Zhe, Wang Yang, Wang Chaohui

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Аннотация

BACKGROUND

Peritoneal metastases (PM) have a poor prognosis in gastric cancer (GC). Cytoreductive surgery (CRS) gives favorable outcomes, but the influence of hyperthermic intraperitoneal chemotherapy (HIPEC) remains contentious. We designed to distinguish results between CRS versus HIPEC-CRS in patients with peritoneal metastases from gastric cancer.

MATERIALS AND

METHODS

PubMed, Scopus, Embase and Cochrane library accessed to collect data and language is restricted to English. RevMan 5.4 was used to perform statistical analysis. The outcomes for categorical variables are mentioned in the risk ratio.

RESULTS

Ten trials involving 1367 patients in which 707 were CRS-HIPEC, while 660 CRS. We got significant results in 3rd year survival (P < 0.05), while 1st and 5th years are not statistically significant P > 0.05.

CONCLUSION

To compare with CRS, CRS-HIPEC has improved survival rate in deprived of further morbidity or mortality.

Для цитирования: Chen Zhuming, Ali Muhammad, Kai Zhe, Wang Yang, Wang Chaohui. HIPEC with CRS versus cytoreductive surgery (CRS) for the gastric cancer metastasis to peritoneum.. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2022. DOI: 10.1007/s12094-022-03004-5.

Предметные рубрики MeSH

Humans Peritoneum Stomach Neoplasms Hyperthermic Intraperitoneal Chemotherapy Peritoneal Neoplasms Combined Modality Therapy Cytoreduction Surgical Procedures Hyperthermia, Induced Survival Rate Antineoplastic Combined Chemotherapy Protocols

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