[Estrogen, androgen and gonadotropin levels in women with encephalo-ophthalmopathies pathogenetically related to thyrotoxicosis].

Thirty-nine young women with encephalopathies pathogenetically related to thyrotoxicosis were examined for the content of sexual hormones and gonadotrophins in the blood by radioimmunoassay and in the urine by physicochemical methods. The content of estradol in the blood plasma of the examined patients remained unchanged whereas the excretion of estrogens with the urine declined. The content of testosterone in the blood plasma and urine increased, excretion of 17-ketosteroids with the urine ascended. The blood content of gonadotrophins, particularly lutrophin, markedly increased. The cure of encephaloophthalmopathy was followed by a tendency toward the attenuation and normalization of the changes detected in the content of sexual hormones and gonadotrophins.