Archivos espanoles de urologia · 2021
[Bladder paraganglioma: Report of two cases and a literature review.].
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
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Pelegrín-Mateo Francisco J, Seguí-Moya Elena, Fernández-Cruz Marian, García-Seguí Alejandro, De Nova-Sánchez Ernesto, Sánchez-Heras Ana Beatriz
Аннотация
OBJECTIVE: Description of two incidental cases of bladder paraganglioma in women and review of the published literature.
METHODS: A bibliographic search was carried out in Medline over the last 10 years according to the terms "urinary bladder" and "paraganglioma".
RESULTS: Bladder paraganglioma (BP) accounts for less than 0.06% of bladder tumors and 10% of all paragangliomas. It may be sporadic or associated with hereditary predisposition syndromes such as Hereditary Paraganglioma- Pheochromocytoma Syndrome. Due to its rarity, there are no recommendations for treatment and monitoring but, their risk of malignancy forces a long-term follow up. The study of germinal mutations through massive sequencing ruled out the association with a hereditary syndrome. Initial management included early reassessment by cystoscopy, transurethral bladder resection (TURB) and imaging.
CONCLUSIONS: Bladder paragangliomas are rare tumors that can be associated to hereditary syndromes. Its treatment and follow - up must be based on a multidisciplinary approach.
METHODS: A bibliographic search was carried out in Medline over the last 10 years according to the terms "urinary bladder" and "paraganglioma".
RESULTS: Bladder paraganglioma (BP) accounts for less than 0.06% of bladder tumors and 10% of all paragangliomas. It may be sporadic or associated with hereditary predisposition syndromes such as Hereditary Paraganglioma- Pheochromocytoma Syndrome. Due to its rarity, there are no recommendations for treatment and monitoring but, their risk of malignancy forces a long-term follow up. The study of germinal mutations through massive sequencing ruled out the association with a hereditary syndrome. Initial management included early reassessment by cystoscopy, transurethral bladder resection (TURB) and imaging.
CONCLUSIONS: Bladder paragangliomas are rare tumors that can be associated to hereditary syndromes. Its treatment and follow - up must be based on a multidisciplinary approach.