[Bladder paraganglioma: Report of two cases and a literature review.].

OBJECTIVE

Description of two incidental cases of bladder paraganglioma in women and review of the published literature.

METHODS

A bibliographic search was carried out in Medline over the last 10 years according to the terms "urinary bladder" and "paraganglioma".

RESULTS

Bladder paraganglioma (BP) accounts for less than 0.06% of bladder tumors and 10% of all paragangliomas. It may be sporadic or associated with hereditary predisposition syndromes such as Hereditary Paraganglioma- Pheochromocytoma Syndrome. Due to its rarity, there are no recommendations for treatment and monitoring but, their risk of malignancy forces a long-term follow up. The study of germinal mutations through massive sequencing ruled out the association with a hereditary syndrome. Initial management included early reassessment by cystoscopy, transurethral bladder resection (TURB) and imaging.

CONCLUSIONS

Bladder paragangliomas are rare tumors that can be associated to hereditary syndromes. Its treatment and follow - up must be based on a multidisciplinary approach.