Archives of pathology & laboratory medicine · 2024
Principles of Analytic Validation of Immunohistochemical Assays: Guideline Update.
СтатьяКлинические рекомендацииНазвание и аннотация: Перевод пока не подготовлен
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Goldsmith Jeffrey D, Troxell Megan L, Roy-Chowdhuri Sinchita, Colasacco Carol F, Edgerton Mary Elizabeth, Fitzgibbons Patrick L, Fulton Regan, Haas Thomas, Kandalaft Patricia L, Kalicanin Tanja, Lacchetti Christina, Loykasek Patti, Thomas Nicole E, Swanson Paul E, Bellizzi Andrew M
Аннотация
CONTEXT.—: In 2014, the College of American Pathologists developed an evidence-based guideline to address analytic validation of immunohistochemical assays. Fourteen recommendations were offered. Per the National Academy of Medicine standards for developing trustworthy guidelines, guidelines should be updated when new evidence suggests modifications.
OBJECTIVE.—: To assess evidence published since the release of the original guideline and develop updated evidence-based recommendations.
DESIGN.—: The College of American Pathologists convened an expert panel to perform a systematic review of the literature and update the original guideline recommendations using the Grading of Recommendations Assessment, Development and Evaluation approach.
RESULTS.—: Two strong recommendations, 1 conditional recommendation, and 12 good practice statements are offered in this updated guideline. They address analytic validation or verification of predictive and nonpredictive assays, and recommended revalidation procedures following changes in assay conditions.
CONCLUSIONS.—: While many of the original guideline statements remain similar, new recommendations address analytic validation of assays with distinct scoring systems, such as programmed death receptor-1 and analytic verification of US Food and Drug Administration approved/cleared assays; more specific guidance is offered for validating immunohistochemistry performed on cytology specimens.
OBJECTIVE.—: To assess evidence published since the release of the original guideline and develop updated evidence-based recommendations.
DESIGN.—: The College of American Pathologists convened an expert panel to perform a systematic review of the literature and update the original guideline recommendations using the Grading of Recommendations Assessment, Development and Evaluation approach.
RESULTS.—: Two strong recommendations, 1 conditional recommendation, and 12 good practice statements are offered in this updated guideline. They address analytic validation or verification of predictive and nonpredictive assays, and recommended revalidation procedures following changes in assay conditions.
CONCLUSIONS.—: While many of the original guideline statements remain similar, new recommendations address analytic validation of assays with distinct scoring systems, such as programmed death receptor-1 and analytic verification of US Food and Drug Administration approved/cleared assays; more specific guidance is offered for validating immunohistochemistry performed on cytology specimens.