Liver growth prediction in ALPPS - A multicenter analysis from the international ALPPS registry.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lopez-Lopez Victor, Linecker Michael, Cruz Juan, Brusadin Roberto, Lopez-Conesa Asuncion, Machado Marcel Autran, Hernandez-Alejandro Roberto, Voskanyan Alejandro Sergey, Li Jun, Balci Deniz, Adam René, Ardiles Victoria, De Santibañes Eduardo, Tomassini Federico, Troisi Roberto I, Lurje Georg, Truant Stéphanie, Pruvot Francois-René, Björnsson Bergthor, Stojanovic Miroslav, Montalti Roberto, Cayuela Valentin, Kozyrin Ivan, Cai Xiujun, de Vicente Emilio, Rauchfuss Falk, Lodge Peter, Ratti Francesca, Aldrighetti Luca, Oldhafer Karl J, Malago Massimo, Petrowsky Henrik, Clavien Pierre-Alain, Robles-Campos Ricardo
Аннотация
METHODS: This cohort study is composed of data derived from the International ALPPS Registry from November 2011 and October 2018. We analyse the influence of demographic, tumour type and perioperative data on the growth of the FLR. The volume of the FLR was calculated in millilitre and percentage using computed-tomography (CT) scans before and after stage 1, both according to Vauthey formula.
RESULTS: A total of 734 patients were included from 99 centres. The median sFLR at stage 1 and stage 2 was 0.23 (IQR, 0.18-0.28) and 0.39 (IQR: 0.31-0.46), respectively. The variables associated with a lower increase from sFLR1 to sFLR2 were age˃68 years (p = .02), height ˃1.76 m (p ˂ .01), weight ˃83 kg (p ˂ .01), BMI˃28 (p ˂ .01), male gender (p ˂ .01), antihypertensive therapy (p ˂ .01), operation time ˃370 minutes (p ˂ .01) and hospital stay˃14 days (p ˂ .01). The time required to reach sufficient volume for stage 2, male gender accounts 40.3% in group ˂7 days, compared with 50% of female, and female present 15.3% in group ˃14 days compared with 20.6% of male.
CONCLUSIONS: Height, weight, FLR size and gender could be the variables that most constantly influence both daily growths, the interstage increase and the standardized FLR before the second stage.