Gan to kagaku ryoho. Cancer & chemotherapy · 2014
[A case of disseminated carcinomatosis of the bone marrow with disseminated intravascular coagulation caused by advanced colon cancer successfully treated with SOX/bevacizumab].
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Suzuki Hiroaki, Matsuoka Nobuko, Ushimaru Yuki, Kakimoto Yoshihito, Toyoda Akira, Endo Yoshitake, Murakami Osamu, Kato Yasuro, Inoue Masafumi, Kimura Takuya, Matsuda Yasuo, Sasakabe Hiroshi
Аннотация
Our patient was a 58-year-old man who was diagnosed with a large bowel obstruction caused by ascending colon cancer, together with multiple liver metastases for which a right hemicolectomy was performed. After the operation, he developed disseminated intravascular coagulation(DIC)and severe anemia. Bone marrow biopsy findings led to a diagnosis of disseminated carcinomatosis of the bone marrow caused by colon cancer. We administered S-1+oxaliplatin(SOX) and bevacizumab( BV)chemotherapy, which improved the DIC. The patient was discharged from the hospital. After a total of six courses of chemotherapy, the carcinoma became resistant. We changed the drug regimen and his clinical condition improved. He survived for 292 days from the onset of disease.