The relationship of mitral valve prolapse to obstructive coronary artery disease. A hemodynamic study.

The relationship between mitral valve prolapse, segmental and total ventricular function was studied in 121 patients with severe coronary artery disease, 21 of whom had angiographically documented mitral prolapse. The position and movement of the inferior papillary muscle were also analyzed. Mitral valve prolapse in association with severe coronary artery disease does not worsen left ventricular function, nor is it related to ischemic wall motion abnormalities.