Terapevticheskii arkhiv · 2004
[Peculiarities of duodenal ulcer with concomitant bronchial asthma (clinical and pathomorphological aspects)].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Cherniavskaia G M, Pleshko R I, Beloborodova E I, Sukhodolo I V, Plekhanova E V
Аннотация
AIM: To study incidence of gastroduodenal ulcer (GDU) in bronchial asthma and clinicomorphological features of ulcer disease in BA in long-term use of systemic corticosteroids (SCS) and without SCS.
MATERIAL AND METHODS: The trial covered 297 BA patients. They have undergone clinicoendoscopic examination of the gastroduodenal zone (GDZ) for duodenal ulcer with assessment of clinical gastroenterological symptoms and morphological analysis of biopsies of gastric and duodenal mucosa using histological, histochemical and morphometric methods.
RESULTS: BA patients were found to have high incidence of duodenal ulcer (21.9%). Morphologically, they had active immune inflammation with hyperergic component. The results of the study did not confirm the opinion about a key role of SCS in development of GDU in BA. Small doses of SCS in patients with BA and GDU do not deteriorate ulcerogenesis.
CONCLUSION: One of the factors determining combination of ulcer disease with BA may be chronic hyperergic inflammation of GDZ mucosa stimulating realization of predisposition to ulcer and its chronic recurrent course.
MATERIAL AND METHODS: The trial covered 297 BA patients. They have undergone clinicoendoscopic examination of the gastroduodenal zone (GDZ) for duodenal ulcer with assessment of clinical gastroenterological symptoms and morphological analysis of biopsies of gastric and duodenal mucosa using histological, histochemical and morphometric methods.
RESULTS: BA patients were found to have high incidence of duodenal ulcer (21.9%). Morphologically, they had active immune inflammation with hyperergic component. The results of the study did not confirm the opinion about a key role of SCS in development of GDU in BA. Small doses of SCS in patients with BA and GDU do not deteriorate ulcerogenesis.
CONCLUSION: One of the factors determining combination of ulcer disease with BA may be chronic hyperergic inflammation of GDZ mucosa stimulating realization of predisposition to ulcer and its chronic recurrent course.